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[b]
Zithromax (Azithromycin) is a semi-synthetic antibiotic, effective against a wide variety of bacteria organisms.[/b]
[/size]
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[b]DESCRIPTION[/b]
Azithromycin tablets belong to a class of medications called macrolide antibiotics. It is used to treat a wide range of infections caused by bacteria, including streptococcal infections of the ear, lungs, skin, and sinuses, and gonococcal and chlamydial infections. It works by stopping bacterial growth.
[b]ORIGINAL USES (ON-LABEL)[/b]
Various bacterial infections.
[b]NEWLY DISCOVERED USES (OFF-LABEL)[/b]
Chlamydia, diarrhea, drug-induced gingival enlargement, prevention of bacterial endocarditis.
[b]POTENTIAL SIDE EFFECTS[/b]
Diarrhea, nausea, rash, abdominal pain, cramping, vomiting.
[b]CAUTIONS[/b]
[list]
[*]Use caution if you have liver dysfunction (symptoms of liver problems may include jaundice, malaise, nausea, vomiting, abdominal colic, and fever). Discontinue use if liver dysfunction occurs.
[*]Use caution if you have developed a certain type of abnormal heart rhythm called QT prolongation prior to therapy.
[*]Safety and efficacy of this drug has not been established in children less than six months of age with acute bacterial infections of the ear, sinus or community-acquired pneumonia, or in children less than two years with tonsillitis.
[/list]
DRUG INTERACTIONS
Pimozide, tacrolimus, phenytoin, ergot alkaloids, alfentanil, bromocriptine, tegretol, cyclosporine, digoxin, disopyramide, triazolam, nelfinavir, antacids containing aluminum or magnesium. Consult your pharmacist or physician before starting any new therapy.
[*]
[b]FOOD INTERACTIONS[/b]
The suspension formulation, but not the tablet form, has increased absorption (46%) with food.
[b]HERBAL INTERACTIONS[/b]
Unknown
[b]PREGNANCY AND BREAST-FEEDING CAUTIONS[/b]
FDA Pregnancy Risk Category B. Azithromycin is excreted in the breast milk and may accumulate. Use with caution during breast-feeding.
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